Interleukin 4 (IL-4) in Urinary Schistosomiasis as a Diagnostic Biomarker During Its Reinfection- A Review

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IL-4 plays a crucial role in regulating oxidative damage in the liver during schistosomiasis.

Liver enlargement and hepatocyte proliferation, normal responses in wild-type (WT) mice infected with the parasitic helminth Schistosoma mansoni, were found to be severely impaired in infected IL-4(-/-) mice. Compared with WT mice, increased levels of O(2)(-), NO, and the more highly reactive ONOO(-) were detected in the liver and produced by lesional cells isolated from liver granulomas of inf...

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Interleukin (IL-15), a pro-inflammatory cytokine has been studied as a possible marker of Alzheimer's disease (AD); however its exact role in neuro-inflammation or the pathogenesis AD is not well understood yet. A Multiple Indicators Multiple Causes (MIMIC) approach was used to examine the relationship between serum IL-15 levels and AD in a well characterized AD cohort, the Texas Alzheimer's Re...

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ژورنال

عنوان ژورنال: International Journal of Clinical and Experimental Medical Sciences

سال: 2017

ISSN: 2469-8024

DOI: 10.11648/j.ijcems.20170305.11